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A Shorter Route to Antibody Binders via Quantitative in vitro Bead-Display Screening and Consensus Analysis

Affinity panning of large libraries is a powerful tool to identify protein binders. However, panning rounds are followed by the tedious re-screening of the clones obtained to evaluate binders precisely. In a first application of Bead Surface Display (BeSD) we show successful in vitro affinity select...

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Detalles Bibliográficos
Autores principales: Mankowska, Sylwia A., Gatti-Lafranconi, Pietro, Chodorge, Matthieu, Sridharan, Sudharsan, Minter, Ralph R., Hollfelder, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098251/
https://www.ncbi.nlm.nih.gov/pubmed/27819305
http://dx.doi.org/10.1038/srep36391