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Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue
OBJECTIVE: Obesity is associated with an increased risk of diabetes mellitus, hypertension, and renal dysfunction. Angiotensin 1–7 and alamandine are heptameric renin angiotensin system peptide hormones. Further, alamandine levels increase with renal dysfunction. In the cardiovascular system, angiot...
Autores principales: | Uchiyama, Tsuyoshi, Okajima, Fumikazu, Mogi, Chihiro, Tobo, Ayaka, Tomono, Shoichi, Sato, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462406/ https://www.ncbi.nlm.nih.gov/pubmed/28591164 http://dx.doi.org/10.1371/journal.pone.0178769 |
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