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Late-onset Alzheimer’s disease is associated with inherent changes in bioenergetics profiles

Body-wide changes in bioenergetics, i.e., energy metabolism, occur in normal aging and disturbed bioenergetics may be an important contributing mechanism underlying late-onset Alzheimer’s disease (LOAD). We investigated the bioenergetic profiles of fibroblasts from LOAD patients and healthy controls...

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Detalles Bibliográficos
Autores principales: Sonntag, Kai-C., Ryu, Woo-In, Amirault, Kristopher M., Healy, Ryan A., Siegel, Arthur J., McPhie, Donna L., Forester, Brent, Cohen, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656579/
https://www.ncbi.nlm.nih.gov/pubmed/29070876
http://dx.doi.org/10.1038/s41598-017-14420-x