Cargando…
Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition
Metabolic viability based high throughput assays like MTT and MTS are widely used in assessing the cell viability. However, alteration in both mitochondrial content and metabolism can influence the metabolic viability of cells and radiation is a potential mitochondrial biogenesis inducer. Therefore,...
Autores principales: | Rai, Yogesh, Pathak, Richa, Kumari, Neeraj, Sah, Dhananjay Kumar, Pandey, Sanjay, Kalra, Namita, Soni, Ravi, Dwarakanath, B. S., Bhatt, Anant Narayan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784148/ https://www.ncbi.nlm.nih.gov/pubmed/29367754 http://dx.doi.org/10.1038/s41598-018-19930-w |
Ejemplares similares
-
PTEN inhibitor bpV(HOpic) confers protection against ionizing radiation
por: Chauhan, Ankit, et al.
Publicado: (2021) -
Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells
por: Bhatt, Anant Narayan, et al.
Publicado: (2015) -
Mitochondrial uncoupler DNP induces coexistence of dual-state hyper-energy metabolism leading to tumor growth advantage in human glioma xenografts
por: Rai, Yogesh, et al.
Publicado: (2022) -
Hexokinase II inhibition by 3-bromopyruvate sensitizes myeloid leukemic cells K-562 to anti-leukemic drug, daunorubicin
por: Rai, Yogesh, et al.
Publicado: (2019) -
Chronic Dietary Administration of the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG) Inhibits the Growth of Implanted Ehrlich’s Ascites Tumor in Mice
por: Singh, Saurabh, et al.
Publicado: (2015)