Cargando…
CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology
BACKGROUND: We aimed to assess the relationship between levels of a cerebrospinal fluid (CSF) marker of pericyte damage, soluble platelet-derived growth factor receptor β (sPDGFRβ) and CSF markers of blood-brain barrier (BBB) integrity (CSF albumin and CSF/serum albumin ratio) and disease pathology...
Autores principales: | Miners, J. S., Kehoe, P. G., Love, S., Zetterberg, H., Blennow, K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745071/ https://www.ncbi.nlm.nih.gov/pubmed/31521199 http://dx.doi.org/10.1186/s13195-019-0534-8 |
Ejemplares similares
-
Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s disease
por: Miners, James, et al.
Publicado: (2023) -
Differing associations between Aβ accumulation, hypoperfusion,
blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the
precuneus and parietal white matter in Alzheimer's disease
por: Miners, J Scott, et al.
Publicado: (2017) -
Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes
por: Cicognola, Claudia, et al.
Publicado: (2023) -
CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease
por: Janelidze, Shorena, et al.
Publicado: (2018) -
CSF metabolites associated with biomarkers of Alzheimer’s disease pathology
por: Dong, Ruocheng, et al.
Publicado: (2023)