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In vivo effects of mutant RHOA on tumor formation in an orthotopic inoculation model
Ras homolog family member A (RHOA) mutations are driver genes in diffuse-type gastric cancers (DGCs), and we previously revealed that RHOA mutations contribute to cancer cell survival and cell migration through their dominant negative effect on Rho-associated kinase (ROCK) signaling in vitro. Howeve...
Autores principales: | Nishizawa, Takashi, Nakano, Kiyotaka, Fujii, Etsuko, Komura, Daisuke, Kuroiwa, Yoshie, Ishimaru, Chisako, Monnai, Makoto, Aburatani, Hiroyuki, Ishikawa, Shumpei, Suzuki, Masami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775816/ https://www.ncbi.nlm.nih.gov/pubmed/31485674 http://dx.doi.org/10.3892/or.2019.7300 |
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