Cargando…

Iron-Chelating Agent Can Maintain Bone Homeostasis Disrupted by Iron Overload by Upregulating Wnt/Beta-Catenin Signaling

BACKGROUND: The incidence of osteoporotic fractures is increasing. In this study, we explored the activities of Wnt/β-catenin signaling in bone tissues with iron accumulation. METHODS: We established rat bipedal walking models (RBWM), and a portion of our RBWM rats were intraperitoneally injected wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Wei, Yu, Ronghua, Zhu, Xiaodong, Li, Zhikun, Jia, Jianjun, Li, Dachuan, Chen, Yu, Zhang, Xiangyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273370/ https://www.ncbi.nlm.nih.gov/pubmed/32596380 http://dx.doi.org/10.1155/2020/8256261

Ejemplares similares

Iron Chelators in Treatment of Iron Overload
por: Entezari, Sarina, et al.
Publicado: (2022)

A Review on Iron Chelators in Treatment of Iron Overload Syndromes
por: Mobarra, Naser, et al.
Publicado: (2016)

Controversies on the Consequences of Iron Overload and Chelation in MDS
por: Vinchi, Francesca, et al.
Publicado: (2020)

Iron Chelation Therapy with Deferasirox in the Management of Iron Overload in Primary Myelofibrosis
por: Elli, Elena Maria, et al.
Publicado: (2014)

Korean Guideline for Iron Chelation Therapy in Transfusion-Induced Iron Overload
por: Jang, Jun Ho, et al.
Publicado: (2013)

Management of transfusional iron overload – differential properties and efficacy of iron chelating agents
por: Kwiatkowski, Janet L
Publicado: (2011)

Effect of iron overload and iron-chelating therapy on allogeneic hematopoietic SCT in children
por: Lee, J W, et al.
Publicado: (2009)

Iron Overload and Breast Cancer: Iron Chelation as a Potential Therapeutic Approach
por: Islam, Sufia, et al.
Publicado: (2022)

Iron Chelator Induces Apoptosis in Osteosarcoma Cells by Disrupting Intracellular Iron Homeostasis and Activating the MAPK Pathway
por: Xue, Yanru, et al.
Publicado: (2021)

Overview of guidelines on iron chelation therapy in patients with myelodysplastic syndromes and transfusional iron overload
por: Gattermann, Norbert
Publicado: (2008)

Iron chelators or therapeutic modulators of iron overload: Are we anywhere near ideal one?
por: Ghosh, Kanjaksha, et al.
Publicado: (2018)

Iron chelation effect of curcumin and baicalein on aplastic anemia mouse model with iron overload
por: Dijiong, Wu, et al.
Publicado: (2019)

Erythrocytapheresis in Children and Young Adults with Hemoglobinopathies and Iron Overload in Need of Iron Chelation Therapy
por: van Hattem, Jessica, et al.
Publicado: (2023)

Iron Overload and Chelation Therapy in Non-Transfusion Dependent Thalassemia
por: Bou-Fakhredin, Rayan, et al.
Publicado: (2017)

Comparison Between Hesperidin, Coumarin, and Deferoxamine Iron Chelation and Antioxidant Activity Against Excessive Iron in the Iron Overloaded Mice
por: Aalikhani, Mahdi, et al.
Publicado: (2022)

Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats
por: Wongjaikam, Suwakon, et al.
Publicado: (2016)

Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy
por: Zarghamian, Parinaz, et al.
Publicado: (2020)

Naringin Chelates Excessive Iron and Prevents the Formation of Amyloid-Beta Plaques in the Hippocampus of Iron-Overloaded Mice
por: Jahanshahi, Mehrdad, et al.
Publicado: (2021)

Chelation Therapy with Oral Solution of Deferiprone in Transfusional Iron-Overloaded Children with Hemoglobinopathies
por: Makis, Alexandros, et al.
Publicado: (2013)

Efficacy and safety of deferasirox, an oral iron chelator, in heavily iron-overloaded patients with β-thalassaemia: the ESCALATOR study
por: Taher, Ali, et al.
Publicado: (2009)

Combination Iron Chelation Therapy with Deferiprone and Deferasirox in Iron-Overloaded Patients with Transfusion-Dependent β-Thalassemia Major
por: Karami, Hossein, et al.
Publicado: (2017)

Improvement of chronic hepatitis B by iron chelation therapy in a patient with iron overload: A case report
por: Zou, Dong-Mei, et al.
Publicado: (2017)

Safety and Efficacy of the New Combination Iron Chelation Regimens in Patients with Transfusion-Dependent Thalassemia and Severe Iron Overload
por: Origa, Raffaella, et al.
Publicado: (2022)

The effects of secondary iron overload and iron chelation on a radiation-induced acute myeloid leukemia mouse model
por: Chan, Lap Shu Alan, et al.
Publicado: (2021)

New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis
por: Feng, Wenya, et al.
Publicado: (2022)

Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis
por: Wang, Hua, et al.
Publicado: (2022)

Iron Chelation Therapy with Deferasirox Results in Improvement of Liver Enzyme Level in Patients with Iron Overload-Associated Liver Dysfunction
por: Miura, Yasuo, et al.
Publicado: (2010)

Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation
por: Rainey, Nathan E., et al.
Publicado: (2019)

The natural iron chelators' ferulic acid and caffeic acid rescue mice's brains from side effects of iron overload
por: AAlikhani, Mahdi, et al.
Publicado: (2022)

From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells
por: Grignano, Eric, et al.
Publicado: (2020)

The Impacts of Iron Overload and Ferroptosis on Intestinal Mucosal Homeostasis and Inflammation
por: Huo, Caiyun, et al.
Publicado: (2022)

Reduction in labile plasma iron during treatment with deferasirox, a once-daily oral iron chelator, in heavily iron-overloaded patients with β-thalassaemia
por: Daar, Shahina, et al.
Publicado: (2009)

Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis
por: Jing, Xingzhi, et al.
Publicado: (2021)

Iron-Storage Protein Ferritin Is Upregulated in Endometriosis and Iron Overload Contributes to a Migratory Phenotype
por: Woo, Jeong-Hwa, et al.
Publicado: (2020)

Single oral dose cure of lethal P. yoelii with a new iron chelator in human clinical trials for iron overload
por: Tripathi, Abhai, et al.
Publicado: (2010)

Iron overload and iron chelating agent exposure in anemia-associated outer retinal degeneration: a case report and review of the literature
por: Belmouhand, Mohamed, et al.
Publicado: (2021)

Management of Iron Overload in Resource Poor Nations: A Systematic Review of Phlebotomy and Natural Chelators
por: Orisakwe, Orish Ebere, et al.
Publicado: (2020)

Chelators for Treatment of Iron and Copper Overload: Shift from Low-Molecular-Weight Compounds to Polymers
por: Hruby, Martin, et al.
Publicado: (2021)

Iron Homeostasis in the CNS: An Overview of the Pathological Consequences of Iron Metabolism Disruption
por: Porras, Christina A., et al.
Publicado: (2022)

Differential Roles of Iron Storage Proteins in Maintaining the Iron Homeostasis in Mycobacterium tuberculosis
por: Khare, Garima, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6sc5f2pqfh9m5o89ev0nek5464