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N-terminal deletion of Swi3 created by the deletion of a dubious ORF YJL175W mitigates protein burden effect in S. cerevisiae
Extreme overproduction of gratuitous proteins can overload cellular protein production resources, leading to growth defects, a phenomenon known as the protein burden/cost effect. Genetic screening in the budding yeast Saccharomyces cerevisiae has isolated several dubious ORFs whose deletions mitigat...
Autores principales: | Saeki, Nozomu, Eguchi, Yuichi, Kintaka, Reiko, Makanae, Koji, Shichino, Yuichi, Iwasaki, Shintaro, Kanno, Manabu, Kimura, Nobutada, Moriya, Hisao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289859/ https://www.ncbi.nlm.nih.gov/pubmed/32528012 http://dx.doi.org/10.1038/s41598-020-66307-z |
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