Nuclear membrane ruptures, cell death, and tissue damage in the setting of nuclear lamin deficiencies

The nuclear membranes function as a barrier to separate the cell nucleus from the cytoplasm, but this barrier can be compromised by nuclear membrane ruptures, leading to intermixing of nuclear and cytoplasmic contents. Spontaneous nuclear membrane ruptures (i.e., ruptures occurring in the absence of...

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Detalles Bibliográficos
Autores principales: Chen, Natalie Y., Kim, Paul H., Fong, Loren G., Young, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529418/
https://www.ncbi.nlm.nih.gov/pubmed/32910721
http://dx.doi.org/10.1080/19491034.2020.1815410