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Transcription factor NF-κB as target for SARS-CoV-2 drug discovery efforts using inflammation-based QSAR screening model
NF-κB is a central regulator of immunity and inflammation. It is suggested that the inflammatory response mediated by SARS-CoV-2 is predominated by NF-κB activation. Thus, NF-κB inhibition is considered a potential therapeutic strategy for COVID-19. The aim of this study was to identify potential an...
Autores principales: | Kanan, Tarek, Kanan, Duaa, Al Shardoub, Ebrahim Jaafar, Durdagi, Serdar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219481/ https://www.ncbi.nlm.nih.gov/pubmed/34311260 http://dx.doi.org/10.1016/j.jmgm.2021.107968 |
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