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Sustained localized delivery of immunotherapy to lymph nodes reverses immunosuppression and increases long-term survival in murine glioblastoma
INTRODUCTION: Despite the advent of immunotherapy as a promising therapeutic, glioblastoma (GBM) remains resistant to using checkpoint blockade due to its highly immunosuppressive tumor milieu. Moreover, current anti-PD-1 treatment requires multiple infusions with adverse systemic effects. Therefore...
Autores principales: | Choi, John, Pant, Ayush, Medikonda, Ravi, Kim, Young-Hoon, Routkevitch, Denis, Saleh, Laura, Tong, Luqing, Chan, Hok Yee, Nedrow, Jessie, Jackson, Christopher, Jackson, Christina, Lim, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274437/ https://www.ncbi.nlm.nih.gov/pubmed/34290904 http://dx.doi.org/10.1080/2162402X.2021.1940673 |
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