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Loss‐of‐function variants in K(v)11.1 cardiac channels as a biomarker for SUDEP
OBJECTIVE: To compare the frequency and impact on the channel function of KCNH2 variants in SUDEP patients with epilepsy controls comprising patients older than 50 years, a group with low SUDEP risk, and establish loss‐of‐function KCNH2 variants as predictive biomarkers of SUDEP risk. METHODS: We se...
Autores principales: | Soh, Ming S., Bagnall, Richard D., Bennett, Mark F., Bleakley, Lauren E., Mohamed Syazwan, Erlina S., Phillips, A. Marie, Chiam, Mathew D. F., McKenzie, Chaseley E., Hildebrand, Michael, Crompton, Douglas, Bahlo, Melanie, Semsarian, Christopher, Scheffer, Ingrid E., Berkovic, Samuel F., Reid, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283159/ https://www.ncbi.nlm.nih.gov/pubmed/34002542 http://dx.doi.org/10.1002/acn3.51381 |
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