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Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection
The majority of HIV infections are established through the genital or rectal mucosa. Fibroblasts are abundant in these tissues, and although not susceptible to infection, can potently enhance HIV infection of CD4+ T cells. Hyaluronic acid (HA) is a major component of the extracellular matrix of fibr...
Autores principales: | Egedal, Johanne H., Xie, Guorui, Packard, Thomas A., Laustsen, Anders, Neidleman, Jason, Georgiou, Konstantinos, Pillai, Satish K., Greene, Warner C., Jakobsen, Martin R., Roan, Nadia R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379073/ https://www.ncbi.nlm.nih.gov/pubmed/33976386 http://dx.doi.org/10.1038/s41385-021-00409-3 |
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