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Bioactive Flavonoids Icaritin and Icariin Protect against Cerebral Ischemia–Reperfusion-Associated Apoptosis and Extracellular Matrix Accumulation in an Ischemic Stroke Mouse Model
Stroke, which is the second leading cause of mortality in the world, is urgently needed to explore the medical strategies for ischemic stroke treatment. Both icariin (ICA) and icaritin (ICT) are the major active flavonoids extracted from Herba epimedii that have been regarded as the neuroprotective...
Autores principales: | Wu, Cheng-Tien, Chen, Man-Chih, Liu, Shing-Hwa, Yang, Ting-Hua, Long, Lin-Hwa, Guan, Siao-Syun, Chen, Chang-Mu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615444/ https://www.ncbi.nlm.nih.gov/pubmed/34829948 http://dx.doi.org/10.3390/biomedicines9111719 |
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