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JAFFAL: detecting fusion genes with long-read transcriptome sequencing
In cancer, fusions are important diagnostic markers and targets for therapy. Long-read transcriptome sequencing allows the discovery of fusions with their full-length isoform structure. However, due to higher sequencing error rates, fusion finding algorithms designed for short reads do not work. Her...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739696/ https://www.ncbi.nlm.nih.gov/pubmed/34991664 http://dx.doi.org/10.1186/s13059-021-02588-5 |