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Mesenchymal stem cells derived from adipose accelerate the progression of colon cancer by inducing a MT-CAFs phenotype via TRPC3/NF-KB axis
BACKGROUND: There is increasing evidence that mesenchymal stem cells (MSCs) help shape the tumor microenvironment and promote tumor progression, and ion channels might play a critical role in this process. The objective of the present study was to explore the function and mechanism of MT-CAFs on pro...
Autores principales: | Xue, Chunling, Gao, Yang, Li, Xuechun, Zhang, Mingjia, Yang, Ying, Han, Qin, Sun, Zhao, Bai, Chunmei, Zhao, Robert Chunhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308187/ https://www.ncbi.nlm.nih.gov/pubmed/35870973 http://dx.doi.org/10.1186/s13287-022-03017-5 |
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