Cargando…
The Presence of EGFR T790M in TKI-Naïve Lung Cancer Samples of Patients Who Developed a T790M-Positive Relapse on First or Second Generation TKI Is Rare
SIMPLE SUMMARY: Treatment outcomes for non-small cell lung cancer (NSCLC) patients have significantly improved since the introduction of targeted therapy using tyrosine kinase inhibitors (TKI). Despite the initial promising results, most patients develop resistance due to on- or off-target mechanism...
Autores principales: | Li, Weiting, Kok, Klaas, Tan, Geok Wee, Meng, Pei, Mastik, Mirjam, Rifaela, Naomi, Scherpen, Frank, Hiltermann, T. Jeroen N., Groen, Harry J. M., van der Wekken, Anthonie J., van den Berg, Anke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320221/ https://www.ncbi.nlm.nih.gov/pubmed/35884570 http://dx.doi.org/10.3390/cancers14143511 |
Ejemplares similares
-
TKI耐药后针对T790M突变治疗
Publicado: (2015) -
Combined therapy with EGFR TKI and gambogic acid for overcoming resistance in EGFR-T790M mutant lung cancer
por: WANG, CHENGDE, et al.
Publicado: (2015) -
The role of T790M mutation in EGFR-TKI re-challenge for patients with EGFR-mutant advanced lung adenocarcinoma
por: Zhang, Qiuyi, et al.
Publicado: (2016) -
Overcoming T790M mutant small cell lung cancer with the third‐generation EGFR‐TKI osimertinib
por: Tang, Kejing, et al.
Publicado: (2018) -
An Observational Study of Acquired EGFR T790M-Dependent Resistance to EGFR-TKI Treatment in Lung Adenocarcinoma Patients in Taiwan
por: Wu, Shang-Gin, et al.
Publicado: (2020)