Construction of PEI‐EGFR‐PD‐L1‐siRNA dual functional nano‐vaccine and therapeutic efficacy evaluation for lung cancer

BACKGROUND: PD‐1/PD‐L1 tumor immunotherapy shows effective anticancer in treatment of solid tumors, so PEI lipid nanoparticles (PEI‐LNP)/siRNA complex (EPV‐PEI‐LNP‐SiRNA) with the therapeutic function of PD‐L1‐siRNA and EGFR short peptide/PD‐L1 double immune‐enhancing function were constructed for t...

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Detalles Bibliográficos
Autores principales: Yang, Guixue, Zhou, Dong, Dai, Yin, Li, Yanqi, Wu, Jiang, Liu, Quanxing, Deng, Xufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626337/
https://www.ncbi.nlm.nih.gov/pubmed/36117149
http://dx.doi.org/10.1111/1759-7714.14618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626337/
https://www.ncbi.nlm.nih.gov/pubmed/36117149
http://dx.doi.org/10.1111/1759-7714.14618

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