Evidence supporting the MICU1 occlusion mechanism and against the potentiation model in the mitochondrial calcium uniporter complex
The mitochondrial calcium uniporter is a Ca(2+) channel that imports cytoplasmic Ca(2+) into the mitochondrial matrix to regulate cell bioenergetics, intracellular Ca(2+) signaling, and apoptosis. The uniporter contains the pore-forming MCU subunit, an auxiliary EMRE protein, and the regulatory MICU...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120041/ https://www.ncbi.nlm.nih.gov/pubmed/37036971 http://dx.doi.org/10.1073/pnas.2217665120 |