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Nano-DMS-MaP allows isoform-specific RNA structure determination
Genome-wide measurements of RNA structure can be obtained using reagents that react with unpaired bases, leading to adducts that can be identified by mutational profiling on next-generation sequencing machines. One drawback of these experiments is that short sequencing reads can rarely be mapped to...
Autores principales: | Bohn, Patrick, Gribling-Burrer, Anne-Sophie, Ambi, Uddhav B., Smyth, Redmond P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250195/ https://www.ncbi.nlm.nih.gov/pubmed/37106231 http://dx.doi.org/10.1038/s41592-023-01862-7 |
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