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Accurate rare variant phasing of whole-genome and whole-exome sequencing data in the UK Biobank
Phasing involves distinguishing the two parentally inherited copies of each chromosome into haplotypes. Here, we introduce SHAPEIT5, a new phasing method that quickly and accurately processes large sequencing datasets and applied it to UK Biobank (UKB) whole-genome and whole-exome sequencing data. W...
Autores principales: | Hofmeister, Robin J., Ribeiro, Diogo M., Rubinacci, Simone, Delaneau, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335929/ https://www.ncbi.nlm.nih.gov/pubmed/37386248 http://dx.doi.org/10.1038/s41588-023-01415-w |
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