Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice

INTRODUCTION: Our goal was to generate xenograft mouse models of human breast cancer based on luciferase-expressing MDA-MB-231 tumor cells that would provide rapid mammary tumor growth; produce metastasis to clinically relevant tissues such as lymph nodes, lung, and bone; and permit sensitive in viv...

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Detalles Bibliográficos
Autores principales: Jenkins, Darlene E, Hornig, Yvette S, Oei, Yoko, Dusich, Joan, Purchio, Tony
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175057/
https://www.ncbi.nlm.nih.gov/pubmed/15987449
http://dx.doi.org/10.1186/bcr1026

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