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The Granzyme B ELISPOT assay: an alternative to the (51)Cr-release assay for monitoring cell-mediated cytotoxicity
BACKGROUND: The interferon-γ (IFN-γ) ELISPOT assay is one of the most useful techniques for immunological monitoring of cancer vaccine trials and has gained increased application as a measure of specific T cell activation. However, it does not assess cell-mediated cytotoxicity directly as IFN-γ secr...
Autores principales: | Shafer-Weaver, Kimberly, Sayers, Thomas, Strobl, Susan, Derby, Eric, Ulderich, Tracy, Baseler, Michael, Malyguine, Anatoli |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC317386/ https://www.ncbi.nlm.nih.gov/pubmed/14697097 http://dx.doi.org/10.1186/1479-5876-1-14 |
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