Cargando…

Unravelling mitochondrial pathways to Parkinson's disease

Mitochondria are essential for cellular function due to their role in ATP production, calcium homeostasis and apoptotic signalling. Neurons are heavily reliant on mitochondrial integrity for their complex signalling, plasticity and excitability properties, and to ensure cell survival over decades. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Celardo, I, Martins, L M, Gandhi, S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Themed Issue: Mitochondrial Pharmacology: Energy, Injury & Beyond
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976614/ https://www.ncbi.nlm.nih.gov/pubmed/24117181 http://dx.doi.org/10.1111/bph.12433

Ejemplares similares

Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease
por: Hall, A R, et al.
Publicado: (2014)

Development of pharmacological strategies for mitochondrial disorders
por: Kanabus, M, et al.
Publicado: (2014)

Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration
por: Osellame, L D, et al.
Publicado: (2014)

Anticonvulsant Medications in Mitochondrial Disease
por: Mithal, Divakar S., et al.
Publicado: (2017)

Biochemical diagnosis of mitochondrial disorders
por: Rodenburg, Richard J. T.
Publicado: (2010)

Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction
por: Koene, Saskia, et al.
Publicado: (2010)

Increased protein propionylation contributes to mitochondrial dysfunction in liver cells and fibroblasts, but not in myotubes
por: Lagerwaard, Bart, et al.
Publicado: (2020)

COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency
por: Martinez Lyons, Anabel, et al.
Publicado: (2016)

De novo mtDNA point mutations are common and have a low recurrence risk
por: Sallevelt, Suzanne C E H, et al.
Publicado: (2017)

Dysregulation of l-arginine metabolism and bioavailability associated to free plasma heme
por: Omodeo-Salè, F., et al.
Publicado: (2010)

Unravelling the dynamics of human development and economic growth on crude oil production based on ARDL and NARDL models
por: Sama, Jean Marie Stevy, et al.
Publicado: (2023)

A new diagnostic indication device of a biomarker growth differentiation factor 15 for mitochondrial diseases: From laboratory to automated inspection
por: Koga, Yasutoshi, et al.
Publicado: (2020)

Anisotropic diffusion of fluorescently labeled ATP in rat cardiomyocytes determined by raster image correlation spectroscopy
por: Vendelin, Marko, et al.
Publicado: (2008)

Pyruvate suppresses PGC1α expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes
por: Philp, Andrew, et al.
Publicado: (2010)

Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm?
por: Ahmed, Asif, et al.
Publicado: (2015)

How Ho Chi Minh City adapted its care pathway to manage the first large-scale community transmission of COVID-19
por: Khue, Luong Ngoc, et al.
Publicado: (2023)

Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury
por: Longo, Diane M, et al.
Publicado: (2019)

Coronavirus disease and home recovery: a Singapore perspective
por: Tan, Hwee Yong Trevor, et al.
Publicado: (2023)

Mitochondrial Toxicity of Cadmium Telluride Quantum Dot Nanoparticles in Mammalian Hepatocytes
por: Nguyen, Kathy C., et al.
Publicado: (2015)

Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells
por: Ball, Amy L., et al.
Publicado: (2016)

Chemogenetic stimulation of the G(i) pathway in astrocytes suppresses neuroinflammation
por: Kim, Jae‐Hong, et al.
Publicado: (2021)

Mitochondrial Toxicity
por: Meyer, Joel N, et al.
Publicado: (2018)

Data generated by evaluating the seasonal variability and trend analysis of the solar energy resource in the Northeastern Brazilian region
por: Martins, Fernando Ramos, et al.
Publicado: (2019)

Evaluation of correlated studies using liquid cell and cryo‐transmission electron microscopy: Hydration of calcium sulphate and the phase transformation pathways of bassanite to gypsum
por: Ilett, M., et al.
Publicado: (2022)

Experiences in COVID-19 clinical management and health-care pathways in the Western Pacific
por: Takaya, Saho, et al.
Publicado: (2023)

Data on PKO biodiesel production using CaO catalyst from Turkey bones
por: Ayoola, A.A., et al.
Publicado: (2018)

Smart campus: Data on energy consumption in an ICT-driven university
por: Popoola, Segun I., et al.
Publicado: (2017)

Parp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson's disease
por: Lehmann, S, et al.
Publicado: (2016)

Generator Maintenance Scheduling using Exchange Market Algorithm
por: Moyo, Learnmore, et al.
Publicado: (2020)

Data set on Rapid Diagnostic Tests (RDTs) and microscopy for diagnosing plasmodium falciparum and plasmodium vivax
por: Olasehinde, Grace I., et al.
Publicado: (2018)

Application of non-uniform film thickness concept in predicting deviated gas wells liquid loading
por: Okoro, Emeka Emmanuel, et al.
Publicado: (2019)

Beyond JAAD October 2020: Articles of interest to dermatologists from the nondermatologic literature
por: Bronin, Andrew, et al.
Publicado: (2020)

Update on the target structures of SARS-CoV-2: A systematic review
por: Prajapat, Manisha, et al.
Publicado: (2020)

Love, wind eggs, and mere conceptions: non-generation in William Harvey’s De conceptione
por: Davis, Isabel
Publicado: (2019)

Alana Ogata credits the role of mentorship in her career decisions
por: Santiago-Maldonado, Xaimara
Publicado: (2022)

Data for crystallisation, dissolution and saturation temperatures of the ternary system: Hexadecane and octadecane representative in fuel solvents
por: Tang, Xue, et al.
Publicado: (2018)

Dataset on information strategies for energy conservation: A field experiment in India
por: Chen, Victor L., et al.
Publicado: (2017)

Experimental data of thermal cracking of soybean oil and blends with hydrogenated fat
por: Beims, R.F., et al.
Publicado: (2018)

Experimental data of the aqueous NH(3) and CO(2) absorption at temperatures from 15 °C to 35 °C, NH(3) concentrations from 5% to 15% and CO(2) loadings from 0.2 to 0.6 measured with the Wetted Wall Column
por: Lillia, Stefano, et al.
Publicado: (2018)

Genetic approaches to metabolic bone diseases
por: Hannan, Fadil M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gmrl438r8764qjemjo550l9nfo