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A major role of insulin in promoting obesity-associated adipose tissue inflammation
OBJECTIVE: Adipose tissue (AT) inflammation is associated with systemic insulin resistance and hyperinsulinemia in obese rodents and humans. A longstanding concept is that hyperinsulinemia may promote systemic insulin resistance through downregulation of its receptor on target tissues. Here we teste...
Autores principales: | Pedersen, David J., Guilherme, Adilson, Danai, Laura V., Heyda, Lauren, Matevossian, Anouch, Cohen, Jessica, Nicoloro, Sarah M., Straubhaar, Juerg, Noh, Hye Lim, Jung, DaeYoung, Kim, Jason K., Czech, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481426/ https://www.ncbi.nlm.nih.gov/pubmed/26137438 http://dx.doi.org/10.1016/j.molmet.2015.04.003 |
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