Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism

We have recently shown that increased hydrogen peroxide (H(2)O(2)) generation is involved in hypoxia–ischemia (HI)-mediated neonatal brain injury. H(2)O(2) can react with free iron to form the hydroxyl radical, through Fenton Chemistry. Thus, the objective of this study was to determine if there was...

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Detalles Bibliográficos
Autores principales: Lu, Qing, Harris, Valerie A., Rafikov, Ruslan, Sun, Xutong, Kumar, Sanjiv, Black, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804102/
https://www.ncbi.nlm.nih.gov/pubmed/26209813
http://dx.doi.org/10.1016/j.redox.2015.06.007

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