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Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism
We have recently shown that increased hydrogen peroxide (H(2)O(2)) generation is involved in hypoxia–ischemia (HI)-mediated neonatal brain injury. H(2)O(2) can react with free iron to form the hydroxyl radical, through Fenton Chemistry. Thus, the objective of this study was to determine if there was...
Autores principales: | Lu, Qing, Harris, Valerie A., Rafikov, Ruslan, Sun, Xutong, Kumar, Sanjiv, Black, Stephen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804102/ https://www.ncbi.nlm.nih.gov/pubmed/26209813 http://dx.doi.org/10.1016/j.redox.2015.06.007 |
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