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Oral Tolerance to Environmental Mycobacteria Interferes with Intradermal, but Not Pulmonary, Immunization against Tuberculosis
Bacille Calmette–Guérin (BCG) is currently the only approved vaccine against tuberculosis (TB) and is administered in over 150 countries worldwide. Despite its widespread use, the vaccine has a variable protective efficacy of 0–80%, with the lowest efficacy rates in tropical regions where TB is most...
Autores principales: | Price, Dominique N., Kusewitt, Donna F., Lino, Christopher A., McBride, Amber A., Muttil, Pavan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859477/ https://www.ncbi.nlm.nih.gov/pubmed/27153120 http://dx.doi.org/10.1371/journal.ppat.1005614 |
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