Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor

Nerve Growth Factor (NGF), the prototype of the neurotrophin family, is essential for maintenance and growth of different neuronal populations. The X-ray crystal structure of NGF has been known since the early '90s and shows a β-sandwich fold with extensive loops that are involved in the intera...

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Detalles Bibliográficos
Autores principales: Paoletti, Francesca, de Chiara, Cesira, Kelly, Geoff, Covaceuszach, Sonia, Malerba, Francesca, Yan, Robert, Lamba, Doriano, Cattaneo, Antonino, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183593/
https://www.ncbi.nlm.nih.gov/pubmed/28083536
http://dx.doi.org/10.3389/fmolb.2016.00083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183593/
https://www.ncbi.nlm.nih.gov/pubmed/28083536
http://dx.doi.org/10.3389/fmolb.2016.00083

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