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Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification
Development of alternative linear peptides for targeting αvβ3 integrin has attracted much attention, as the traditional peptide ligand, cyclic RGD, is limited by inferior water-solubility and complex synthesis. Using pharmacophore-based virtual screening and high-throughput molecular docking, we ide...
Autores principales: | Ma, Yi, Ai, Guanhua, Zhang, Congying, Zhao, Menglu, Dong, Xue, Han, Zhihao, Wang, Zhaohui, Zhang, Min, Liu, Yuxi, Gao, Weidong, Li, Siwen, Gu, Yueqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436510/ https://www.ncbi.nlm.nih.gov/pubmed/28529634 http://dx.doi.org/10.7150/thno.18401 |
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