Cargando…
Histamine H3R receptor activation in the dorsal striatum triggers stereotypies in a mouse model of tic disorders
Tic disorders affect ~5% of the population and are frequently comorbid with obsessive-compulsive disorder, autism, and attention deficit disorder. Histamine dysregulation has been identified as a rare genetic cause of tic disorders; mice with a knockout of the histidine decarboxylase (Hdc) gene repr...
Autores principales: | Rapanelli, M, Frick, L, Pogorelov, V, Ohtsu, H, Bito, H, Pittenger, C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545743/ https://www.ncbi.nlm.nih.gov/pubmed/28117842 http://dx.doi.org/10.1038/tp.2016.290 |
Ejemplares similares
-
White matter abnormalities in the Hdc knockout mouse, a model of tic and OCD pathophysiology
por: Jindachomthong, Kantiya, et al.
Publicado: (2022) -
Histamine and the striatum
por: Bolam, J. Paul, et al.
Publicado: (2016) -
Inhibition of CREB Activity in the Dorsal Portion of the Striatum Potentiates Behavioral Responses to Drugs of Abuse
por: Fasano, Stefania, et al.
Publicado: (2009) -
Altered dopaminergic regulation of the dorsal striatum is able to induce tic-like movements in juvenile rats
por: Nespoli, Ester, et al.
Publicado: (2018) -
A Guide to Childhood Motor Stereotypies, Tic Disorders and the Tourette Spectrum for the Primary Care Practitioner
por: Mills, Sarah, et al.
Publicado: (2014)