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miR-99 regulates normal and malignant hematopoietic stem cell self-renewal
The microRNA-99 (miR-99) family comprises a group of broadly conserved microRNAs that are highly expressed in hematopoietic stem cells (HSCs) and acute myeloid leukemia stem cells (LSCs) compared with their differentiated progeny. Herein, we show that miR-99 regulates self-renewal in both HSCs and L...
Autores principales: | Khalaj, Mona, Woolthuis, Carolien M., Hu, Wenhuo, Durham, Benjamin H., Chu, S. Haihua, Qamar, Sarah, Armstrong, Scott A., Park, Christopher Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551568/ https://www.ncbi.nlm.nih.gov/pubmed/28733386 http://dx.doi.org/10.1084/jem.20161595 |
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