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Dectin-1/2–induced autocrine PGE(2) signaling licenses dendritic cells to prime Th2 responses
The molecular mechanisms through which dendritic cells (DCs) prime T helper 2 (Th2) responses, including those elicited by parasitic helminths, remain incompletely understood. Here, we report that soluble egg antigen (SEA) from Schistosoma mansoni, which is well known to drive potent Th2 responses,...
Autores principales: | Kaisar, Maria M. M., Ritter, Manuel, del Fresno, Carlos, Jónasdóttir, Hulda S., van der Ham, Alwin J., Pelgrom, Leonard R., Schramm, Gabriele, Layland, Laura E., Sancho, David, Prazeres da Costa, Clarissa, Giera, Martin, Yazdanbakhsh, Maria, Everts, Bart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927467/ https://www.ncbi.nlm.nih.gov/pubmed/29668708 http://dx.doi.org/10.1371/journal.pbio.2005504 |
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