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Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures
BACKGROUND: There is increasing appreciation that non-cancer cells within the tumour microenvironment influence cancer progression and anti-cancer drug efficacy. For metastatic prostate cancer (PCa), the bone marrow microenvironment influences metastasis, drug response, and possibly drug resistance....
Autores principales: | Mosaad, Eman, Chambers, Karen, Futrega, Kathryn, Clements, Judith, Doran, Michael Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968610/ https://www.ncbi.nlm.nih.gov/pubmed/29793440 http://dx.doi.org/10.1186/s12885-018-4473-8 |
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