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Initial Clinical Experience of RP5063 Following Single Doses in Normal Healthy Volunteers and Multiple Doses in Patients with Stable Schizophrenia

RP5063 is a multimodal dopamine (D)‐serotonin (5‐HT) stabilizer with a high affinity for D(2/3/4) and 5‐HT(1A/2A/2B/7) receptors and moderate affinity for the serotonin transporter. Single‐dose (10 and 15 mg fasting, 15 mg fed) safety in healthy volunteers and multiple‐dose (10, 20, 50, and 100 mg f...

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Detalles Bibliográficos
Autores principales: Cantillon, Marc, Ings, Robert, Bhat, Laxminarayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039200/
https://www.ncbi.nlm.nih.gov/pubmed/29637739
http://dx.doi.org/10.1111/cts.12545

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