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Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks
Histone posttranslational modifications (PTMs) regulate chromatin dynamics, DNA accessibility, and transcription to expand the genetic code. Many of these PTMs are produced through cellular metabolism to offer both feedback and feedforward regulation. Herein we describe the existence of Lys and Arg...
Autores principales: | Galligan, James J., Wepy, James A., Streeter, Matthew D., Kingsley, Philip J., Mitchener, Michelle M., Wauchope, Orrette R., Beavers, William N., Rose, Kristie L., Wang, Tina, Spiegel, David A., Marnett, Lawrence J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140490/ https://www.ncbi.nlm.nih.gov/pubmed/30150385 http://dx.doi.org/10.1073/pnas.1802901115 |
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