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A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer

The envelope protein of human immunodeficiency virus-1 (HIV-1) and its fusion peptide are essential for cell entry and vaccine design. Here, we describe the 3.9-Å resolution structure of an envelope protein trimer from a very early transmitted founder virus (CRF01_AE T/F100) complexed with Fab from...

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Detalles Bibliográficos
Autores principales:	Ananthaswamy, Neeti, Fang, Qianglin, AlSalmi, Wadad, Jain, Swati, Chen, Zhenguo, Klose, Thomas, Sun, Yingyuan, Liu, Yue, Mahalingam, Marthandan, Chand, Subhash, Tovanabutra, Sodsai, Robb, Merlin L., Rossmann, Michael G., Rao, Venigalla B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382815/ https://www.ncbi.nlm.nih.gov/pubmed/30787293 http://dx.doi.org/10.1038/s41467-019-08825-7

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