Cargando…
The Mechanics of Translocation: A Molecular “Spring-and-Ratchet” System
The translation of genetic information into proteins is a fundamental process of life. Stepwise addition of amino acids to the growing polypeptide chain requires the coordinated movement of mRNA and tRNAs through the ribosome, a process known as translocation. Here, we review current understanding o...
Autores principales: | Moran, Stephen J., Flanagan, John F., Namy, Olivier, Stuart, David I., Brierley, Ian, Gilbert, Robert J.C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119126/ https://www.ncbi.nlm.nih.gov/pubmed/18462671 http://dx.doi.org/10.1016/j.str.2008.04.001 |
Ejemplares similares
-
Direct Observation of Distinct A/P Hybrid-State tRNAs in Translocating Ribosomes
por: Flanagan, John F., et al.
Publicado: (2010) -
A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting
por: Namy, Olivier, et al.
Publicado: (2006) -
Experimental study of a nanoscale translocation ratchet
por: Molcrette, Bastien, et al.
Publicado: (2022) -
Electrostatic Ratchet in the Protective Antigen Channel Promotes Anthrax Toxin Translocation
por: Wynia-Smith, Sarah L., et al.
Publicado: (2012) -
Kif15 functions as an active mechanical ratchet
por: McHugh, Toni, et al.
Publicado: (2018)