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Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity
The transcription factor RORα plays an important role in regulating circadian rhythm, inflammation, metabolism, and cellular development. Herein we show a role for RORα-expressing macrophages in the adipose tissue in altering the metabolic state of mice on a high-fat diet. The expression of Rora and...
Autores principales: | Hams, Emily, Roberts, Joseph, Bermingham, Rachel, Hogan, Andrew E., O'Shea, Donal, O'Neill, Luke, Fallon, Padraic G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482427/ https://www.ncbi.nlm.nih.gov/pubmed/32973801 http://dx.doi.org/10.3389/fimmu.2020.01966 |
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