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Improved computational analysis of ribosome dynamics from 5′P degradome data using fivepseq
In eukaryotes, 5′–3′ co-translation degradation machinery follows the last translating ribosome providing an in vivo footprint of its position. Thus, 5′ monophosphorylated (5′P) degradome sequencing, in addition to informing about RNA decay, also provides information regarding ribosome dynamics. Mul...
Autores principales: | Nersisyan, Lilit, Ropat, Maria, Pelechano, Vicent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685019/ https://www.ncbi.nlm.nih.gov/pubmed/33575643 http://dx.doi.org/10.1093/nargab/lqaa099 |
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