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Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity
Dendritic cells are sentinels of the immune system and represent a key cell in the activation of the adaptive immune response. Hypoxia-inducible factor 1 alpha (HIF-1α)–a crucial oxygen sensor stabilized during hypoxic conditions–has been shown to have both activating and inhibitory effects in immun...
Autores principales: | Tran, Charles W., Gold, Matthew J., Garcia-Batres, Carlos, Tai, Kelly, Elford, Alisha R., Himmel, Megan E., Elia, Andrew J., Ohashi, Pamela S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775062/ https://www.ncbi.nlm.nih.gov/pubmed/33382742 http://dx.doi.org/10.1371/journal.pone.0244366 |
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