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Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo
The bone marrow (BM) stroma in myeloid neoplasms is altered and it is hypothesized that this cell compartment may also harbor clonal somatically acquired mutations. By exome sequencing of in vitro expanded mesenchymal stromal cells (MSCs) from n = 98 patients with myelodysplastic syndrome (MDS) and...
Autores principales: | Jann, Johann-Christoph, Mossner, Maximilian, Riabov, Vladimir, Altrock, Eva, Schmitt, Nanni, Flach, Johanna, Xu, Qingyu, Nowak, Verena, Obländer, Julia, Palme, Iris, Weimer, Nadine, Streuer, Alexander, Jawhar, Ahmed, Darwich, Ali, Jawhar, Mohammad, Metzgeroth, Georgia, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546146/ https://www.ncbi.nlm.nih.gov/pubmed/34697318 http://dx.doi.org/10.1038/s41467-021-26424-3 |
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