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Modeling of Personalized Treatments in Colon Cancer Based on Preclinical Genomic and Drug Sensitivity Data
SIMPLE SUMMARY: This experimental preclinical study developed a strategy to identify signatures for the personalized treatment of colon cancer focusing on target-specific drug combinations. Tumor growth inhibition was analyzed in a preclinical phase II study using 25 patient-derived xenograft models...
Autores principales: | Keil, Marlen, Conrad, Theresia, Becker, Michael, Keilholz, Ulrich, Yaspo, Marie-Laure, Lehrach, Hans, Schütte, Moritz, Haybaeck, Johannes, Hoffmann, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656546/ https://www.ncbi.nlm.nih.gov/pubmed/34885128 http://dx.doi.org/10.3390/cancers13236018 |
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