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Semi-synthetic puwainaphycin/minutissamide cyclic lipopeptides with improved antifungal activity and limited cytotoxicity
Microbial cyclic lipopeptides are an important class of antifungal compounds with applications in pharmacology and biotechnology. However, the cytotoxicity of many cyclic lipopeptides limits their potential as antifungal drugs. Here we present a structure–activity relationship study on the puwainaph...
Autores principales: | Hájek, Jan, Bieringer, Sebastian, Voráčová, Kateřina, Macho, Markéta, Saurav, Kumar, Delawská, Kateřina, Divoká, Petra, Fišer, Radovan, Mikušová, Gabriela, Cheel, José, Fewer, David P., Vu, Dai Long, Paichlová, Jindřiška, Riepl, Herbert, Hrouzek, Pavel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041360/ https://www.ncbi.nlm.nih.gov/pubmed/35498921 http://dx.doi.org/10.1039/d1ra04882a |
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