Cargando…
A combined computational and experimental investigation of the filtration function of splenic macrophages in sickle cell disease
Being the largest lymphatic organ in the body, the spleen also constantly controls the quality of red blood cells (RBCs) in circulation through its two major filtration components, namely interendothelial slits (IES) and red pulp macrophages. In contrast to the extensive studies in understanding the...
Autores principales: | Li, Guansheng, Qiang, Yuhao, Li, He, Li, Xuejin, Buffet, Pierre A., Dao, Ming, Karniadakis, George Em |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312537/ https://www.ncbi.nlm.nih.gov/pubmed/37398427 http://dx.doi.org/10.1101/2023.05.31.543007 |
Ejemplares similares
-
Patient-specific modeling of individual sickle cell behavior under transient hypoxia
por: Li, Xuejin, et al.
Publicado: (2017) -
Quantitative prediction of erythrocyte sickling for the development of advanced sickle cell therapies
por: Lu, Lu, et al.
Publicado: (2019) -
How the spleen reshapes and retains young and old red blood cells: A computational investigation
por: Li, He, et al.
Publicado: (2021) -
Mechanics of diseased red blood cells in human spleen and consequences for hereditary blood disorders
por: Li, He, et al.
Publicado: (2018) -
Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease
por: Qiang, Yuhao, et al.
Publicado: (2023)