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Neuron-specific chromatin disruption at CpG islands and aging-related regions in Kabuki syndrome mice
Many Mendelian developmental disorders caused by coding variants in epigenetic regulators have now been discovered. Epigenetic regulators are broadly expressed, and each of these disorders typically exhibits phenotypic manifestations from many different organ systems. An open question is whether the...
Autores principales: | Boukas, Leandros, Luperchio, Teresa Romeo, Razi, Afrooz, Hansen, Kasper D., Bjornsson, Hans T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418197/ https://www.ncbi.nlm.nih.gov/pubmed/37577516 http://dx.doi.org/10.1101/2023.08.01.551456 |
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