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Multidimensional scaling methods can reconstruct genomic DNA loops using Hi-C data properties
This paper proposes multidimensional scaling (MDS) applied to high-throughput chromosome conformation capture (Hi-C) data on genomic interactions to visualize DNA loops. Currently, the mechanisms underlying the regulation of gene expression are poorly understood, and where and when DNA loops are for...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434948/ https://www.ncbi.nlm.nih.gov/pubmed/37590265 http://dx.doi.org/10.1371/journal.pone.0289651 |