Cargando…
Exploring CAR-T Cell Therapy Side Effects: Mechanisms and Management Strategies
Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of malignancies, especially hematological tumors, but toxicities have tempered its success. The main impediments to the development of CAR-T cell therapies are the following: cytokine release syndrome (CRS), immune-effec...
Autores principales: | Zhang, Yugu, Qin, Diyuan, Shou, Arthur Churchill, Liu, Yanbin, Wang, Yongsheng, Zhou, Lingyun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10573998/ https://www.ncbi.nlm.nih.gov/pubmed/37834768 http://dx.doi.org/10.3390/jcm12196124 |
Ejemplares similares
-
gC1qR: A New Target for Cancer Immunotherapy
por: Lei, Yanna, et al.
Publicado: (2023) -
Potential lung attack and lethality generated by EpCAM-specific CAR-T cells in immunocompetent mouse models
por: Qin, Diyuan, et al.
Publicado: (2020) -
Targeting sphingosine 1-phosphate receptor 3 inhibits T-cell exhaustion and regulates recruitment of proinflammatory macrophages to improve antitumor efficacy of CAR-T cells against solid tumor
por: Gao, Ge, et al.
Publicado: (2023) -
Mechanisms of cytokine release syndrome and neurotoxicity of CAR T-cell therapy and associated prevention and management strategies
por: Xiao, Xinyi, et al.
Publicado: (2021) -
Complementary Strategies for the Management of Radiation Therapy Side Effects
por: Stubbe, Christine E., et al.
Publicado: (2013)