A Viral microRNA Down-Regulates Multiple Cell Cycle Genes through mRNA 5′UTRs

Global gene expression data combined with bioinformatic analysis provides strong evidence that mammalian miRNAs mediate repression of gene expression primarily through binding sites within the 3′ untranslated region (UTR). Using RNA induced silencing complex immunoprecipitation (RISC-IP) techniques...

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Detalles Bibliográficos
Autores principales: Grey, Finn, Tirabassi, Rebecca, Meyers, Heather, Wu, Guanming, McWeeney, Shannon, Hook, Lauren, Nelson, Jay A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891821/
https://www.ncbi.nlm.nih.gov/pubmed/20585629
http://dx.doi.org/10.1371/journal.ppat.1000967

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