Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

BACKGROUND: The PFD1235w Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigen is associated with severe malaria in children and can be expressed on the surface of infected erythrocytes (IE) adhering to ICAM1. However, the exact three-dimensional structure of this PfEMP1 and its surf...

Descripción completa

Detalles Bibliográficos
Autores principales: Victor, Michala E, Bengtsson, Anja, Andersen, Gorm, Bengtsson, Dominique, Lusingu, John P, Vestergaard, Lasse S, Arnot, David E, Theander, Thor G, Joergensen, Louise, Jensen, Anja TR
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994891/
https://www.ncbi.nlm.nih.gov/pubmed/21078147
http://dx.doi.org/10.1186/1475-2875-9-325

Ejemplares similares