Cargando…
Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer
BACKGROUND: SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ovarian cancer. We hypothesized that single nucleotide polymo...
Autores principales: | Han, Chan H, Huang, Yu-Jing, Lu, Karen H, Liu, Zhensheng, Mills, Gordon B, Wei, Qingyi, Wang, Li-E |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025876/ https://www.ncbi.nlm.nih.gov/pubmed/21214932 http://dx.doi.org/10.1186/1756-9966-30-5 |
Ejemplares similares
-
Secreted Sulfatases Sulf1 and Sulf2 Have Overlapping yet Essential Roles in Mouse Neonatal Survival
por: Holst, Charles R., et al.
Publicado: (2007) -
Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation
por: Okada, Takuya, et al.
Publicado: (2017) -
Context Dependent Sulf1/Sulf2 Functional Divergence in Endothelial Cell Activity
por: Justo, Tiago, et al.
Publicado: (2022) -
Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage
por: Otsuki, Shuhei, et al.
Publicado: (2008) -
Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity
por: Kalus, Ina, et al.
Publicado: (2009)